Histoid leprosy is a skin condition, a rare form of multibacillary leprosy See also[edit]. Leprosy · Skin lesion. References[edit]. ^ James, William D.; Berger. Histoid leprosy, an uncommon variant of lepromatous leprosy, develops usually as relapse in lepromatous patients who are on dapsone. Summary Histoid leprosy is a rare multibacillary form that presents with disseminated papule-nodular cutaneous lesions. To study the inflammatory infiltrate.

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De-novo Histoid Leprosy

Histoid leprosy is a skin condition, a rare form of multibacillary leprosy. Closer view of Figure 1 Click here to view.

It exhibits a fibromatoid tendency in the chronic form. There was history of low-grade fever for 15 days, associated with redness, pain and discharge from eye, and nasal stuffiness.

Views Read Edit View history. Articles which use leprost templates with no data rows Infobox medical condition new All stub articles.

Herein, we present a case of lfprosy 37 year old male who presented with skin coloured raised lesions mainly over the trunk, chest, neck and ears in contrast to its oeprosy site of presentation, associated with tingling sensation over the hands and feet. Histoid lepromas are sudden eruption of dome shaped lesions usually associated with dapsone resistance, as a variant of lepromatous leprosy or rarely arising de novo.

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Histoid leprosy is an uncommon entity with specific clinical, histopathological and bacteriological features.

De Novo Histoid Leprosy in an Elderly: A Case Report and Review of the Literature

Each of them can be differentiated from histoid Hansen on the basis of the characteristic histopathology, absence of mycobacteria on slit skin smear, and nerve thickening.

Erythema nodosum leprosum rarely occurs in histoid Hansen. Initial reports were associated with dapsone resistance and with relapse after dapsone monotherapy. Lesions vary in size and consistency. Histoid, a clinical variant of multibacillary leprosy: How to cite this URL: A retrospective study of 40 cases from India.

Histoid Leprosy

FNAC is a simple cost-effective method of investigation that is more useful in tuberculoid, lperosy, and histoid leprosy patients. Histoid leprosy A Review.

Discussion Histoid leprosy is considered a variant of lepromatous lepros 2 ] and by others as a distinct entity. It usually occurs in lepromatous patients, after dapsone monotherapy or rarely as de novo. Received Nov; Accepted Feb.

Histoid leprosy is known to occur in patients on anti — leprosy treatment or as a variant of lepromatous leprosy.

There was no thickening of peripheral nerves. A report of three cases. These cases may act as reservoirs of the hishoid and lead to further spread of leprosy. A year-old man, an agriculturist by occupation, complained of multiple nodules all over the body, associated with itching over the skin since one year.


Sehgal VN, Srivastava G. There was no history of fever, pain, epistaxis, pedal edema, altered sensations or long-term drug intake for the same. Histoid leprosy as reservoir of the disease; a challenge to leprosy elimination. Relapse as histoid leprosy after multidrug receiving therapy MDT: National Center for Biotechnology InformationU. Fite’s stain from FNAC is also positive in case of histoid leprosy, which must stimulate interest for further studies.

An increase in both cell-mediated and humoral immunity against Mycobacterium lepraeas in lepromatous leprosy, has been hypothesized. Reports are available with pronounced involvement of the face, the ears may show little change or may be unaffected [ 15 ]. Case Reports in Pathology.

Histoid Hansens clinically simulates dermatofibromas, xanthomas, neurofibromas, reticulohistiocytosis, and cutaneous metastasis. This case highlights the importance of FNAC in all similar cases where spindle cell nodular lesions of the leeprosy are encountered. Lepromatous leprosy of histoid type.